Myelin purity

The composition of myelin is well characterized because it can be isolated in high yield and purity by subcellular fractionation 56 Central nervous system myelin is enriched in certain lipids 56 Peripheral and central nervous system myelin lipids are qualitatively similar 58... 

Severe neurotoxicity was reported in rats as a result of 7 days of continuous inhalation exposure to 225 ppm 2-hexanone (Couri et al. 1977). However, no data for this toxic effect were given in the study. Paralysis was observed in rats exposed to 225 ppm 2-hexanone (purity not stated) for 9.5 weeks or to 400 ppm for 6 weeks (Saida et al. 1976). Inpouchings of the myelin sheath of the... 

Nistor GI, Totoiu MO, Haque N, Carpenter MK, Keirstead HS (2005) Human embryonic stem cells differentiate into oligodendrocytes in higlr purity and myelinate after spinal cord transplantation. Glia 49 385-396. 

It has been difficult to establish criteria for the purity of myelin because only recently have workers developed an a posteriori description of essential constituents of the substance. There are a few biochemical markers that are... 

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