Mutation Research Kirkland

Kirkland, D. and Speit, G. (2008) Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens III. Appropriate followup testing in vivo. Mutation Research, 654, 114-132. 

Kirkland DJ and Muller L (2000) Interpretation of the biological relevance of genotoxicity test results The importance of thresholds. Mutational Research 464(1) 137-147. 

Kirkland, D. and Marzin, D. (2003). An assessment of the genotoxicity of 2-hydroxy-1,4-naphthoquinone, the natural dye ingredient of heima. Mutation Research, 537, 183-199. 

Kirkland, D., Reeve, L., Gatehouse, D., Vanparys, P. (2011). A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins. Mutation Research, 721, 27-73. 

Pfuhler S, Kirkland D, Kasper P, Hayashi M, Vanparys P, Carmichael P, et al. Reduction of use of animals in regnlatory genotoxicity testing Identification and implementation opportnnities-Report from an ECVAM workshop. Mutation Research. 2009 680 (1-2) 31 2. 

Lorge, E., Hayashi, M., Albertini, S., Kirkland, D. (2008). Comparison of different methods for an accurate assessment of cytotoxicity in the in vitro micronucleus test I. Theoretical aspects. Mutation Research, Vol. 655, pp. 1-3, ISSN 0027-5107 Lypez-Otin, C, Matrisian, RM (2007). Emerging roles of proteases in tumour suppression. 

Kirkland, D. J., and Dean, S. W. On the need for confirmation of negative genotoxicity results in vitro and on the usefulness of mammalian cell mutation tests in a core battery Experiences of a contract research laboratory. Mutagenesis 9, 491-501,1994. 

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