Mutation cytochrome P450 monooxygenase

Imai, M., Shimada, H., Watanabe, Y., Matsushima-Hibiya, Y., Makino, R., Koga, H., Horiuchi, T., and Ishimura, Y., 1989, Uncoupling of the cytochrome P450 cam monooxygenase reaction by a single mutation, threonine-252 to alanine or valine A possible role of the hydroxy amino acid in oxygen activation, Proc. Natl. Acad. Sci. USA 86 782367827. 

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