Muse - Alprostadil

Intraurethral Alprostadil MUSE 125-1000 meg 5-10 minutes prior to intercourse0 Two times daily... [Pg.784]

Intraurethral Alprostadil (MUSE) 125-mcg 250-mcg 500-mcg 1,000-mcg pellet 125-1,000 meg 5-10 minutes before intercourse... [Pg.951]

Alprostadil, IntracavOTiosal (Cavaject, Edex) Alprostadil, Urethral Suppository (Muse) Ammonium Aluminum Sulfate [Alum] BeUadonna Opium Suppositories (B O Supprettes)... [Pg.57]

Erectile dysfunction Alprostadil Muse Polyethylene glycol 1450... [Pg.224]

The incidence of priapism after intracorporeal administration of alprostadil is 1%. Priapism after medicated urethral system for erection (MUSE) has been reported (16). [Pg.115]

A 57-year-old man with erectile impotence, who had previously been treated with intracorporeal injections of papaverine and alprostadil, resulting in recurrent episodes of priapism necessitating aspiration, decided to try intraurethral alprostadil (MUSE). The dose needed to achieve a full erection in the clinic was titrated to 1 ig, but after 5 months this was found to be inadequate unless supplemented by a hot bath before MUSE administration. The patient stated that with MUSE alone the erection lasted for 5-10 minutes but on the two previous occasions when he had had a hot bath for 20 minutes and then used MUSE, the erection had lasted 3-4 hours. However, on the third occasion, priapism lasted 20 hours and necessitated corporeal aspiration for detumescence. [Pg.115]

Williams G, Abbou CC, Amar ET, Desvaux P, Flam TA, Lycklama a Nijeholt GA, Lynch SF, Morgan RJ, Muller SC, Porst H, Pryor JP, Ryan P, Witzsch UK, Hall MM, Place VA, Spivack AP, Todd LK, Gesundheit N. The effect of transurethral alprostadil on the quality of life of men with erectile dysfunction, and their partners. MUSE Study Group. Br J Urol 1998 82(6) 847-54. [Pg.115]

Alprostadil Caveqect Muse Pharmacia Upjohn AstraZeneca PGE, Ductus arteriosus 50-100 ngkg min Erectile dysfunction 5-20 fxg intracavemosally Erectile dysfunction 125-1000 fig intraurethrally... [Pg.300]

Intraurethral Alprostadil (MUSE) 125-mcg, 250-mcg, 500-mcg, 1000-mcg pellets 125-1000 meg 5 to 10 minutes before intercou rse... [Pg.1521]

Alprostadil is commercially available as an intracavernosal injection (Caverject and Edex) and as an intraurethral insert (medicated urethral system for erection MUSE). [Pg.1526]

Intraurethral alprostadil inserts are marketed as MUSE, which contains a pellet inside a prefllled urethral applicator. Multiple studies show this product to have an overall effectiveness rate of 43% to 60%, " as compared with 70% to 90% for intracavernosal alprostadil. Its decreased effectiveness and inconvenient administration method have resulted in this product being considered a second-line treatment option for patients with erectile dysfunction. However, some patients respond to intraurethral alprostadil even when intracavernosal alprostadil did not work for them. ... [Pg.1529]

FIGURE 81-8. Technique for administration of intraurethral alprostadil with a MUSE appi icator. Reprinted with permission from Kirby R, Carson C, Goldstein I. Erectile Dysfunction, A Clinical Guide. Oxford, England, ISIS Medical Media, 1999 62.)... [Pg.1529]

Porst El. Transurethral alprostadil with MUSE (medicated urethral system for erection) vs intracavernous alprostadil—A comparative study in 103 patients with erectile dysfunction. Int J Impot Res 1997 9 187-192. [Pg.1533]

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