Muscle structure excitation-contraction coupling

Babiychuk EB, Draeger A 2000 Annexins in cell membrane dynamics. Ca2+-regulated association of lipid microdomains. J Cell Biol 150 1113-1124 Ber DM 2001 Excitation-contraction coupling and cardiac contractile force, 2nd edn. Kluwer Academic Publishers, Dordrecht/Boston/London Blaustein MP, Golovina VA 2001 Structural complexity and functional diversity of endoplasmic reticulum Ca2+ stores. Trends Neurosci 24 602—608 Flynn ER, Bradley KN, Muir TC, McCarron JG 2001 Functionally separate intracellular Ca2+ stores in smooth muscle. J Biol Chem 276 36411-36418 Fry CH, WuCl 997 Initiation of contraction in detrusor smooth muscle. Scand J Urol Nephrol Suppl 184 7-14... 

Triadins, a multiprotein family with different distribution of the various splice variants within the sarcoplasmic reticulum (SR). Their function may include involvement in excitation-contraction coupling, in triad targeting, in structural function, or in muscle differentiation. Triadin, a glycoprotein (Mr 95 kDa) expressed in both skeletal and cardiac muscle, was first identified in rabbit skeletal muscle involved in calcium release for muscle contraction. Recently, it has been reported that triadins are not triad-specific proteins. Two new skeletal muscle triadins may be involved in the architecture of the SR [I. Marty, Cell. Mol. Life Sci. 2004, 61, 1850 S. VassHopoulos etal, J. Biol. Chem. 2005, 280, 28601]. 

Many of the effects of eicosanoids are calcium dependent and their structure has stimulated speculation that they may act as calcium iono-phores (Horton 1969, Harris et al. 1979, Kirtland and Baum 1972). With reference to excitation-contraction coupling in smooth muscle, some workers have found that prostaglandin-induced smooth muscle contraction is dependent on extracellular calcium (Smith et al. 1981, Godfraind and Miller 1982) whereas others have suggested that such a contraction is mediated by a release of calcium from intracellular stores (McNamara et al. 

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