Multivariate statistical models 548 INDEX

Quantitative Structure Activity Relationships (QSAR) and Modeling Society. URL http //www.ndsu.nodak.edu/qsar soc/index.htm. Classical QSAR, multivariate statistical modeling, molecular modeling, computer-aided drug design, and environmental chemistry. [Pg.37]

A homogeneity index or significance coefficienf has been proposed to describe area or spatial homogeneity characteristics of solids based on data evaluation using chemometrical tools, such as analysis of variance, regression models, statistics of stochastic processes (time series analysis) and multivariate data analysis (Singer and... [Pg.129]

A more detailed analysis using multivariable regression of the ibuprofen data demonstrated that a three-parameter model accurately fit the data (Table 7). The Bonding Index and the Heywood shape factor, a, alone explained 86% of the variation, while the best three-variable model, described in what follows, explained 97% of the variation and included the Bonding Index, the Heywood shape factor, and the powder bed density. All three parameters were statistically significant, as seen in Table 7. Furthermore, the coefficients are qualitatively as... [Pg.308]