Multivalent structures residues

Figure 7.2 Schematic representation of alginate cross-linking with divalent cations and the chemical structure of the constituent repeat units, guluronate (G) and mannuronate (M). Carboxylate groups present along the backbone (largely from the G residues) interact with multivalent cations to yield metal ion cross-linked gels.

The other procedure described for the generation of multivalent globotriaose dendrimers for protection against VTl or VT2 cytotoxicity in vivo is based on carbosilane multimers (183). These multimers are more systematic expansions of trimeric structures that are based on multiples of the tetrameric carbosilane (184). In these studies, coupling the two terminal silicon residues of a linear carbosilane trimer ( super twig ) to either... 

J. L. Asensio, F. J. Canada, H.-C. Siebert, J. Laynez, A. Poveda, P. M. Nieto, U. M. S. Soedjanaatmadja, H.-J. Gabius, and J. Jimenez-Barbero, Structural basis for chitin recognition by defense proteins GlcNAc residues are bound in a multivalent fashion by extended binding sites in hevein domains, Chem. Biol, 1 (2000) 529-543. 

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