Multiplex gas chromatography

The first report on the concept of thermal modulation was published in 1985 by Phillips s group [26]. By then, the modulation principle was not yet involved in GC xGC but rather in the so-called multiplex gas chromatography concept that was used in the field of headspace sampling without preconcentration for low-level analytes. On-column thermal desorption modulation was then applied in the field of sample introduction as a device capable of narrow injection pulses for high-speed GC [27]. 

Quantitative Measurements of Endogenous and Deuterium Tracer Variants of Drugs and Metabolites Using a Multiplexed Gas Chromatography/ Quadrupole Mass Spectrometer Proc. Int. Conf. Stable Isotop. 

Yang, M.J. and Pawliszyn, J. Headspace membrane extraction combined with multiplex gas chromatography and mass selective detector for monitoring of volatile organic compounds. Journal of Microcolumn Separations 1996, 8 (2), 89-98. 

Wong, K.S. (2003) The application of multiplexed microemulsion electrokinetic chromatography for the rapid determination of log Pow values for neutral and basic compounds. Liquid Chromatography and Gas Chromatography of North America, 21, 1078-1088. 

Up to 64 gas chromatographs are simultaneously connected (in tirae-shciring) to a small or medium computer whose hardware and software is specially designed for gas chromatography. The voltage of the instruments is successively sampled by a multiplexer and stored in the core. To save... 

The most characteristic s)mibol of comprehensive two-dimensional gas chromatography (and of any other "comprehensive" coupling) is the multiplex (x), used to abbreviate its full name to GCxGC. Most of the nomenclature and symbols used in GCxGC which are now widely accepted were included by Schoenmakers et al. in a 2003 publication [6]. Their suggestions are used throughout this book. 

For the reader who is interested in pursuing the mathematical details of CC, I recommend the papers of Smit and his co-workers (15) These researchers published early in the area of CC (16) and continue to contribute regularly to the field (17) Phillips has also been active in the field of CC, which he considers to be a subset of what he calls, multiplex chromatography (18). Some workers have used on-line correlation chromatography to study the thermal decomposition of polymers and compared the results against those using conventional injection procedures (19), while others have applied it to the study of gas-solid adsorption (20) ... 

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