Multiplex advantage spectrometry

In the absence of fluctuation noise, the multiplex advantage of FT-IR spectrometry over a single-channel dispersive spectrometer with the same optical throughput and efficiency (often referred to as Fellgett s advantage) is given by the square root of the number of resolution elements in the spectrum, M, where M =... 

Obviously, the combination of element labeling and then detection by element mass spectrometry is still in its infancy for quantitative proteomics. However, this is such a promising method for metallomics and metallopro-teomics, because of the unique advantages (1) results can be validated due to the traceability of ICP-MS measurement (2) multiplexed analysis is easy to implement because of the availability of so many isotopes for labeling and (3) absolute quantification at a very low concentration allows comparison between the results from different laboratories. 

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