Mouse antibodies recovery

Reactors of this type have been used to produce and harvest the heavy chain of a murine monoclonal antibody using protein G affinity and histidine-tagged human granulocyte-macrophage colony-stimulating factor (GM-CSF) using metal affinity chromatography. Implementation of this scheme on a small scale was difficult, but these studies show that the amount of recoverable protein can be increased [62]. As shown in Fig. 4, recoveries of human GM-CSF and a mouse monoclonal antibody heavy chain were increased by three- and seven-fold, re-... 

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