Montgomery-Asberg Depression Rating Scale

Montgomery Asberg Depression Rating Scale (MADRS l (Hamilton. 1959 Montgomery and Asberg, 1979). 

Of 33 patients with chronic hepatitis C treated with interferon alfa, 9 MU/week for 3-12 months, prospectively evaluated using the Montgomery-Asberg Depression Rating Scale (MADRS) before and after 12 weeks of treatment, eight developed depressive symptoms, of whom four had major depression without a previous psychiatric history (381). All four recovered after treatment with antidepressants. This study confirmed that a high baseline MADRS is significantly associated with the occurrence of depressive symptoms. 

Montgomery Asberg Depression Rating Scale (MADRS) Clinician-rated 10-item, 7-point scale. Eor each item 0 = no symptoms 6 = severe symptoms Differentiates between all the intermediate grades of depression. Decreases bias in patients with other medical illness and increased somatization... 

Observational studies In a 6-week, prospective, unrandomized, open study in 20 patients with acute bipolar depression, aripiprazole up to a maximum of 30 mg/ day improved Montgomery-Asberg Depression Rating Scale (MADRS) and Mania Rating Scale (MRS) scores significantly [64 ]. The most fi-equent adverse reactions were nausea and akathisia two patients withdrew because of akathisia. 

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