Monolayers of Bile Acids and Other Amphiphiles

Mixed Monolayers of Bile Acids and Other Amphiphiles 

Two methods have been used to study molecular interaction in mixed films. In the first, binary mixtures of two insoluble components are spread on the surface of the substrate and compression isotherms obtained. In the second method (111), an insoluble component is spread and a soluble substance is injected into the aqueous phase. After allowing a given time for the soluble substance to equilibrate with the surface, an isotherm is obtained. The interpretation of the latter studies is often difficult and the scope of this review does not permit a thorough discussion of the studies that have been carried out (112). 

Representative curves for mixtures of lecithin and lithocholic acid spread 

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B. Mixed Monolayers of Bile Acids and Other Amphiphiles... 

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