Chloromethylation with monochloromethyl ether

Methoxymethyl derivatives of polysilanes, which cannot be obtained from the corresponding chloromethyl compounds by nucleophilic substitution because of intramolecular rearrangement, are prepared successfully by the reaction of chloropolysilanes with monochloromethyl ether in the presence of magnesium in tetrahydrofuran. 

Anion exchange membranes can be made from the same crosslinked polystyrene membrane base by post-treatment with monochloromethyl ether and aluminum chloride to introduce chloromethyl groups into the benzene ring, followed by formation of quaternary amines with trimethyl amine ... 

Ya on and co-workers measured comparative chloromethylation rates for a number of aromatics b following the reaction of these compounds with monochloromethyl ether in glacial acetic acid. This reaction is shown in the follow ing equation, in which RH stands for an aromatic hydrO carbon ... 

The chloromethylation of 2,6-dimethyl- and 2,5-diethyl-thiophene both with chlorodimethyl ether and formaldehyde and hydrochloric acid gives a mixture of mono- and di-chloromethylated product. " The former reagent gives the larger proportion of monochloromethyl-ated product. " If the chloromethylation is carried out in the presence of zinc chloride, (120) and (121) are obtained. ... 

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