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Monobactams

By screening strains of bacteria that were specifically responsive to p-lactam antibiotics, monobactams, varying in substitution at the C-3 position, were identified. The structures of the compounds along with their producing organisms are shown in Table 1. More recendy, the 4P-methyl analogue (4, R = CH3) of SQ 26,445/sulfazecin (4, R = H) was isolated using a differential antibacterial assay (3). [Pg.60]

Organism Monobactam CAS Registry Molecular formula Structure number [Pg.60]

Kirk-Othmer Encyclopedia of Chemical Technology (4th Edition) [Pg.60]

Absolute configuration CAS Registry Number Molecular formula MIC, Rg/mLb [Pg.61]

The biosynthetic origin of monobactams has been elucidated by fermentation experiments using radioactively labeled amino acids (qv). The [Pg.61]

ANTTBIOTTCS - BETA-LACTAMS - MONOBACTAMS] (Vol 3) l-Amino-2,7-naphthalenedisulfomc acid [486-54-4]... [Pg.44]

Monoazo dyes Monoazo salts Monoazo yellow pigments Monobactams... [Pg.645]

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Biosynthesis of the Monobactams

Bridged monobactams

Monobactam

Monobactam

Monobactam antibiotics

Monobactam antibiotics Mannich reaction

Monobactam antibiotics Monomerine

Monobactam antibiotics Monosaccharides

Monobactam antibiotics conjugate addition

Monobactam antibiotics synthesis

Monobactams and

Monobactams biosynthesis

Monobactams, synthesis

Structure-Activity Relationship among Bridged Monobactams

X-Ray Structure of the Complex with a Bridged Monobactam

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