Molecular recognition sensor array

Hirsch T, Kettenberger H, Wolfbeis OS, Mirsky VM. A simple strategy for preparation of sensor arrays molecularly structured monolayers as recognition elements. Chem Commun 2003 432-433. 

Suslick KS, Rakow NA, Sen A. Colorimetric sensor arrays for molecular recognition. Tetrahedron 2004 60 11133-8. 

Figure 5.28 Four imprinted polymers tested in an array against three different analytes to produce different patterns of recognition. N. T. Greene, S. L. Morgan and K. D. Shimizu, Molecularly imprinted polymer sensor arrays, Chem. Commun, 2004, 1 172-1 173. Reproduced by permission of The Royal Society of Chemistry.

Numerous examples are found in the literature of analyte detection using EAP systems. Arrays of EAPs are used in biomolecular recognition schemes, resulting in devices known as electronic noses and electronic tongues (371-373) that mimic the mammalian sensor receptors. EAPs functionalized to contain polyalkyl ether and crown ether moieties (374-378) or polymerized in the presence of polyelectrolyte dopants (379) have been used to detect a variety of ions (Li+, Na+, K+, Ba +, Mg +, Cs+, Zn +, Cu+, NR4+) (see Fig. 15). EAPs have also been prepared with enantioselectivity toward chiral dopant ions (380,381) and fimctionalized for molecular recognition (382). 

Grate JW (2000) Acoustic wave microsensor arrays for vapor sensing. Chem Rev 100 2627-2647 Grate JW, Patrash SJ, Abraham MH, Du CM (1996) Selective vapor sorption by polymers and cavitands on acoustic wave sensors is this molecular recognition Aneil Chem 68 913-917 Gutsche CD (1989) Calixarene. The Royal Society of Chemistry, Cambridge... 

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