Molecular recognition of DNA

Minehan, T.G., K. Gottwald, and P.B. Dervan. Molecular recognition of DNA by Hoechst benzimidazoles Exploring beyond the pyrrole-imidazole-hydroxypyr-role polyamide-pairing code. Helv. Chim. Acta. 2000, 83, 2197-2213 and references cited therein. 

DNA-Modified Electrodes. Molecular Recognition of DNA and Biosensor Applications... 

Haruta O, Matsuo Y, Hashimoto Y, Niikura K, Ijiro K. 2008. Sequence specific control of azobenzene assemblies by molecular recognition of DNA. Langmuir 24 2618 2625. 

Dervan PB (2001) Molecular recognition of DNA by small molecules. Bioorg Med Chem 9(9) 2215-2235... 

Deubel, D. V. (2003). Reactivity of osmium tetraox-ide towards nitrogen heterocycles Implications for the molecular recognition of DNA mismatch. Angewandte Chemie International Edition, 42, 1974. 

Ohlendorf, D.H., et al. The molecular basis of DNA-protein recognition inferred from the structure of Cro repressor. Nature 298 718-723, 1982. 

Recognition of DNA sequence and molecular design of artificial repressors, pyrrole-imidazole polyamides, and calicheamycin derivatives 97YGK384. 

Recognition of DNA sequence and DNA bending and molecular design for artificial repressors 97YGK384. 

Molecular mechanisms of DNA recognition and function by bioactive compounds 00YZ1409. 

Simulation of the calicheamicin/esperamicin cascade has been amply demonstrated by Danishefsky and co-workers with a variety of compounds (Scheme 7-49) [219-221]. Furthermore, comparisons of ealicheamicin yj (2) and calicheamicinone (222) in DNA-cleavage experiments pointed to the importance of the carbohydrate fragment of the natural product in the molecular recognition of its target sequence [85]. 

Self-assembly and molecular recognition of some biomolecules lead to lyotropic liquid-crystalline behavior with water [5]. These molecular complexes derived from biomolecules could be more important in view of biofunction. Nucleic acids such as DNA and RNA, which self-organize supramolecular complexes, show lyotropic mesophases [5]. Complexes of nucleic acid and cationic amphiliphic molecules form mesomorphic molecular arrangements, which can be used for drug delivery such as gene therapy [6]. 

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