Molecular computers based on synthon interactions

1000 A. Chemists would be able to o down to the hundreds or even tens of A Besides, the new technology would be based on self-organization (supramole-cular chemistry) and self-assembling. In 1 cm we could store the information of a huge number of todays CD-ROMs. People thought a computer had to have the form of a box with metallic and non-metallic tools inside, as it is now. However. 

In 1994 mathematieian Leonard M. Adleman began his experiments in one polymerase of the Ameriean geneties labs, while learning the biological stuff in the evenings. 

Therefore, it was certain that the polymerase and the DNA (and eertainly some other moleeules) eould be used as eomputers. If we think about it now, the eom-puter in our head is more similar to excusez le mot water, than to a box with hard disks, ete. The aehievement of Adleman was that he was able to translate a known and important mathematieal problem into the language of laboratory reeipes, and then using a ehemieal proeedure he was able to solve the mathematieal problem. 

William Rowan HamiHon (1805-1865) was a Astronomer Royal in Ireland. At the age of 17 he found an error in the l ous Celestial Mechanics by Laplace. This drew the attention of scientists and was the beginning of the Hamilton s scierrtrfic career. In the present book his name is repeated many times (because of Hamiltonian). 

Let us recall two important examples of complementary synthons guanine and cytosine (GC) and adenine with tymine, see p. 751. 

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