Moldular Synthesis of Block Copolymers

Problem 12.5 Show how an ABC triblock terpolymer, poly(methyl acrylate)-f -polystyrene-f -poly(tm-butyl acrylate) (PMMA-fc-PSt-fc-PtBA), can be synthesized modularly, in a controlled manner, using ATRP and consecutive CuAAC coupling reactions. 

As the nal step in preparing the triblock terpolymer, TIPS-S-PMA-N3 (1.5 equiv) is coupled to the free end functionality of the H-=-PSt-( -PtBA-Br diblock copolymer via CuAAC reaction, which is conducted at 50°C with CuBr/Me TREN as the Cu(I) source and DMF as the solvent (Opsteen and van Hest, 2007). The excess of azide functionalized PMA is again removed by reduction of the azide moiety with PPh3 and extraction of the amine terminated polymer with the mixed solvent CH2Cl2/MeOH (95 5). 

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