Modern microwave synthesizers

According to Scheme 2.1 the principles of green chemistry can be condensed to the word productively [16]. Two main goals are to eliminate or minimize the use of volatile organic solvents in modern syntheses and to reduce energy inputs. Development of new synthetic solvent-free methods with microwave assistance is an important topic of research with growing popularity, because solvent-free reactions reduce solvents usage, simplify synthesis and separation procedures, prevent waste, and avoid the hazards and toxicity associated with the use of solvents [135]. 

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