Modeling of drug release

Siepmann, J. and Peppas, N., Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC), Advanced Drug Delivery Reviews, Vol. 48, No. 2-3, 2001, pp. 139-157. [Pg.387]

Kanjickal, D. G, and Lopina, S. T. (2004), Modeling of drug release from polymeric delivery systems—a review, Crit. Rev. Ther. Drug Carrier Syst., 21(5), 345-386. [Pg.562]

Husson, I., Leclerc, B., Spenlehauer, G., Veillard, M., and Couarraze, G. (1991), Modeling of drug release from pellets coated with an insoluble polymeric membrane, J. Controlled Release, 17,163-173. [Pg.1217]

The classic diffusion model of drug release, when matrix degradation is neglected, can be written as (6,18)... [Pg.83]

Grassi M, Lapasin R, and Pricl S. Modeling of drug release from a sweUable matrix. Chem. Eng. Comm. 1998 169 79-109. [Pg.466]

Singh M, Lumpkin JA, and Rosenblatt J. Mathematical modeling of drug release from hydrogel matrices via a diffusion coupled with desorption mechanism. J. Control. Rel. 1994 32 17-25. [Pg.467]

Sirotti C, Colombo I, and Grassi M. Modeling of drug release from polydispersed microencapsulated spherical particles. J. Microencapsulation 2002 19(5) 603-614. [Pg.468]

Ford, J.L., Mitchell, K., Rowe, R, Armstrong, D.J., Elliott, P.N.C., Rostron, C. and Hogan, J.E. (1991) Mathematical modelling of drug release from hydroxypropylmethylceUulose matrices effect of temperature. Int J Pharm, 71, 95-104. [Pg.240]

Faisant N, Siepmann J, Richard J, et al. Mathematical modeling of drug release from bioerodible microparticles effect of gamma-irradiation. Eur J Pharm Biopharm 2003 56 271-279. [Pg.21]

Kaunisto, E., Manicci, M., Borgquist, P., Axelsson, A., 2011. Mechanistic modelling of drug release from polymer-coated and swelling and dissolving polymer matrix systems. International Journal of Pharmaceutics 418, 54—77. [Pg.150]

Thombre, A.G. and Himmclstein, K.J. (1984) Modelling of drug release kinetics from laminated device hat ing an erodible drug reseiv oir, Biomalerials. 5, 250-254. [Pg.473]

Aggarwal AK, Jain S (2011) Physicochemical characterization and dissolution study of solid dispersions of ketoconazole with nicotinamide. Chem Pharm Bull 59 629-638 Ahuja N, Katare OP, Singh B (2007) Studies on dissolution enhancement and mathematical modeling of drug release of a poorly water-soluble drug using water-soluble carriers. Eur J Pharm... [Pg.634]

In the modelling of drug release from matrix systems, several important factors must be eonsidered, namely the shape of the device, the state of the drug (dissolved/ dispersed) within the polymeric matrix and the loading of drug. Aceordingly, the effect of these factors on drug release will be briefly considered. [Pg.25]

Mathematical modelling of drug release from biodegradable systems requires consideration of the relative rates of polymer degradation and drug diffusion. Two defined scenarios may be established, as described next. [Pg.31]

C.S. Brazel, N.A. Peppas, Modeling of drug release from swellable polymers, European... [Pg.120]

C. Sirotti, I. Colombo, and M. Grassi, Modelling of drug-release from poly-disperse micro-encapsulated spherical particles,/owma/ of Microencapsulation, 19 (5), 603-614,2002. [Pg.278]

Petrovic, S. Ibric, C. Betz,). Parojcic, and Z. Duric, Application of dynamic neural networks in the modeling of drug release from polyethylene oxide matrix tablets, Eur. J. Pharm. Sci., 3S, 172-180, 2009. [Pg.361]

Figure 8.46(a) Simulation model of drug release from the sample (droplet matrix) in an in vitro cell with membrane filter separating A from C. [Pg.545]

Figure 9 Model of drug releases from core-shell electrospun fibers (a) sPLA-cPEG/GS and...

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