Model GPSVS

Caco-2 permeability prediction, based on an experimental model (Caco-2 cells monolayer) that evaluates the intestinal absorption of drugs [30], is derived from known literature datasets - see [31] for a review. This model was confirmed with GPSVS. 

Water solubility (thermodynamic) prediction, based on various literature datasets [32, 33], is comparable to other models [29]. This model was confirmed with GPSVS. 

ChemGPS-VolSuif (GPSVS) in Clinical PK Property Modeling I 2S7... 

PGA models are usually interpreted by comparing descriptor loadings (their contribution) to the latent variables, which relate to physical meaning. However, in GPSVS, the first two components are directly related to measured properties. 

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