Mixtures unlimited separability

Under unlimited separability, we understand possible separation from the mixture of any component or a component group (fractions) with any purity (i.e., with the preset negligibly small amounts of other impurity components). 

There are two classes of mixtures that are not characterized by unlimited separability the azeotropic mixtures and the thermolabile ones. 

Chankvetadze et al. have demonstrated the potential of flow-counterbalanced capillary electrophoresis (FCCE) in chiral and achiral micropreparative separations [27], Unlimited increase of separation selectivity can be achieved for binary mixtures, such as (+ )-chlorpheniramine with carboxymethyl-(3-cyclodextrin chiral selector, or a- and (3-isomers of a asparatame dipeptide. The carrier of the chiral selector or pseudo-stationary phase, electroosmotic flow (EOF), pressure-driven flow, or hydrodynamic flow can be used as a counterbalancing flow to the electrophoretic mobility of the analyte or vice versa, resulting in dramatic changes of the effective mobilities of the sample mixture components [28], This approach can be used for micropreparative CE, stepwise separations, and fraction collection of multicomponent mixtures [27],... 

Gases generally possess unlimited capacity to mix together. Such mixtures do not separate as long as both components are in the gas phase. There are, however, some gas mixtures that have limited intermiscibility, that is, a mixing gap. A two-component example is the mixture of ammonia and nitrogen, whose solubility diagram is shown in Fig. 4-15. Note, however, the extreme conditions under which this phenomenon occurs. 

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