Mitscherlichii

This pale-yellow quaternary alkaloid, picrate mp 189°, [a]D of chloride — 930° (in water), was first isolated from a calabash curare (12) it was subsequently isolated from other calabash curare preparations (34, 35) and has been identified chromatographically in extracts from the bark of S. mitscherlichii (33) and other Strychnos species (7). The identification of C-fluorocurarine is greatly helped by its deep-blue fluorescence in UV-light. Analyses of the crystalline iodide and anthraquinone sulfonate showed its molecular formula to be C2oH23N20+ (12), which is in agreement with all subsequent work. The properties of C-fluorocurarine, particularly its low toxicity and high Rc values, suggest that it is a C20 alkaloid rather than a double molecule. This was confirmed (102) by application of the partial quaternization method to one of its derivatives (see subsequent discussion) the method cannot be applied to C-fluorocurarine itself, since on pyrolysis it is not smoothly demethylated to the... 

Strychnos mitscherlichii R. Schomb. (Strychnos smilacina Benth.)... 

S. mitscherlichii Rob. Schomb. var. mitscherlichii is another large climber reaching more than 30 m in length and a diameter of up to 10 cm it occurs in a variety of habitats, including high forest on terra firme. It is found in Colombia, Venezuela, Guiana, and Amazonian and eastern Brazil (108, 217,... 

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