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Mitotic Segregation

At the time of cell division, the proportion of mutant and wild-type mtDNAs in the two daughter cells can shift, thus giving them different genotypes and, possibly, different phenotypes, a phenomenon called mitotic segregation. [Pg.707]

Crebelli R, Conti G, Carere A. 1987. On the mechanism of mitotic segregation induction in Aspergillus nidulans by benzene hydroxy metabolites. Mutagenesis 2 235-238. [Pg.207]

Parmar, D., Srivastava, S.P., Singh, G.B. Seth, PK. (1995) Testicular toxicity of di(2-ethylhexyl) phthalate in developing rats. Vet. hum. Toxicol., 37, 310-313 Party, E.M. (1985) Tests for the effects on mitosis and the mitotic spindle in Chinese hamster primary liver cells (CHl-L) in cnlture. Prog. Mutat. Res., 5, 479 85 Party, J.M. Eckardt, F. (1985) The detection of mitotic gene conversion, point mutation and mitotic segregation nsing the yeast Saccharomyces cerevisiae strain D7. Prog. Mutat. Res., 5, 261-269... [Pg.141]

Parry, J.M. Eckardt, F. (1985a) The detection of mitotic gene conversion, point mutation and mitotic segregation using the yeast Saccharomyces cerevisiae strain D7. Prog. Mutat. Res., 5,261-269... [Pg.101]

Phenol weakly induced mitotic segregation in Aspergillus nidulans. [Pg.757]

ANG, Aspergillus nidulans P1, mitotic segregation - NT 336 Crebelli etal. (1988)... [Pg.1522]

There are several limitations in using primary cell lines from patients with mitochondrial disease (e.g., fibroblasts and myoblasts) (Jl). They are not immortal, and usually grow very slowly in regular culture media. Some of the cell lines do not retain a fully physiological, differentiated phenotype in culture. In addition, they tend to lose mutant mtDNA as a result of mitotic segregation (Jl). Most importantly, one cannot rule out the effect of the nuclear background on the phenotypic expression of mitochondrial dysfunction under examination. [Pg.108]

Kafer, E., B.R. Scott, G.L. Dorn, and R. Stafford. Aspergillus nidulans Systems and results of tests for chemical induction of mitotic segregation and mutation. I. Diploid and duplication assay systems. [Pg.268]

Mitotic segregation of alleles High frequency Low frequency... [Pg.315]

Forbes, E. (1959), Use of mitotic segregation for assigning genes to linkage groups in Aspergillus nidulans. Heredity 13, 67-80. [Pg.72]

Mapping in yeast may also be accomplished by a random spore procedure avoiding the need to manipulate asci [69, 70] and by analysis of mitotic segregants [68, 70]. [Pg.173]

See other pages where Mitotic Segregation is mentioned: [Pg.231]    [Pg.316]    [Pg.114]    [Pg.114]    [Pg.434]    [Pg.434]    [Pg.435]    [Pg.435]    [Pg.377]    [Pg.264]    [Pg.19]   


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