Misexpression studies

Two subsequent studies by Kauret al. (1992) and McLain et al. (1992) used the same p-actin promoter to drive misexpression of the Hox-2.2... 

Reverse genetic approaches start with a sequence and attempt to identify a function for the gene. This can be done by using PCR-based screens on DNA from insertionally mutagenized populations, ectopic misexpression of the gene, and expression studies, e.g., with RT-PCR or microarray analyses. 

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