Miscellaneous Reactions Involving Silver Carbenoids

Mechanistically, most alkyne cyclizations of this type have been interpreted in terms of the catalyst serving as a Lewis acid, activating the n bond to nucleophilic attack,53-57 and while this pathway is feasible, the authors preferred one involving the intermediacy of a silver carbene.52 Control studies ruled out a pathway involving 

Our own endeavors in this area have been possible because of the hard work and valuable intellectual contributions of a number of coworkers, whose names appear in the references. Financial support has generously been provided by The Robert A. Welch Foundation (Y-1362). 

Issue number 8 of Chemical Reviews (Chem. Rev. 2008,108) was devoted to the utility of coinage metals in synthesis. 

We use the term carbene transfer to represent the net chemical transformation and not necessarily to imply that this is a reactive intermediate (either a free carbene or a metallo-carbene). 

Migita, T. Ando, W. Kondo, S. Matsuyama, H. Kosugi, M., Nippon Kagaku Zasshi 1970, 91, 374-377. 

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