Minimal infectious dose

The effect of vitamin E on immune responses and disease resistance is now well established and has been covered in recent reviews (Axelrod, 1978 Nockels, 1978 Sheffy and Schultz, 1979 Tengerdy, 1978). Predictably, vitamin E ([dl])-a-tocophery1-acetate) deficiency leads to impaired immune response and disease protection (Axelrod, 1978). Large doses of vitamin E, much larger than the presently accepted recommended minimal daily allowance, on the other hand, enhance certain immune responses and can lead to increased disease resistance in a number of animal species against a variety of infectious agents. Table I. illustrates this point. 

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