Mikolajczyk

J. Drabowicz and M. Mikolajczyk, in Proceedings of the First International Symposium on Cyclodextrins (Ed. J. Szejtli), Reidel, Dordrecht, 1982, pp. 205-215 Chem. Abstr., 98, 71128g (1983). 

M. Mikolajczyk and J. Drabowicz reported by JD at the 12th International Symposium on the Organic Chemistry of Sulfur, 29 June-4 July, 1986, Nijmegen, The Netherlands and personal communication. 

JOZEF DRABOWICZ, PIOTR KIELBASINSKI AND MARIAN MIKOLAJCZYK... 

A different non-classical approach to the resolution of sulphoxides was reported by Mikolajczyk and Drabowicz269-281. It is based on the fact that sulphinyl compounds very easily form inclusion complexes with /1-cyclodextrin. Since /1-cyclodextrin as the host molecule is chiral, its inclusion complexes with racemic guest substances used in an excess are mixtures of diastereoisomers that should be formed in unequal amounts. In this way a series of alkyl phenyl, alkyl p-tolyl and alkyl benzyl sulphoxides has been resolved. However, the optical purities of the partially resolved sulphoxides do not exceed 22% after... 

The Mikolajczyk group36 has developed use of natural alkaloids as chiral catalysts in conversion of symmetrical dialkyl sulfites into alkyl t-butylsulfinate esters in 40-70% enantiomeric purity (equation 6). 

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