MIKES energy spectrometry

A) MASS-ANALYSED ION KINETIC ENERGY SPECTROMETRY (MIKES)... 

The structure of the radical cation [CaHsN] (102) has been established by mass-analyzed ion kinetic energy spectrometry (MIKE) (780MS518). From structure (103), structures (104) and (105) are formed (Scheme 4). 

Mass-analysed ion kinetic energy spectrometry (MIKES) A form of MS-MS product-ion scan that may be carried out on a reversed-geometry double-focusing mass spectrometer. 

MIKES Mass-analysed ion kinetic energy spectrometry... 

MIKES Mass-analysed Ion Kinetic Energy Spectrometry CAR Collision-Activated Reaction... 

A similar technique applicable to reverse geometry mass spectrometers (magnetic sector before electrostatic analyser) is that of mass-analysed ion kinetic energy spectrometry (MIKES). In this technique the ion to be studied is isolated by the magnet and induced to fragment by collision activation in a small chamber filled with a gas such as helium. The product ions are then detected by scanning the electrostatic analyser voltage. 

Mass-analyzed ion kinetic energy spectrometry, collision-induced dissociation (MIKES/CID) spectral studies conducted on l,3,5,7-tetranitro-l,3,5,7-tetrazocane (HMX) and 1,3,5,7-tetroxocane showed the presence of a series of cyclic multimers <85JA7228>. 

In sector instruments with reversed geometry, product ion scanning as depicted above is known as MIKES (mass-analyzed ion kinetic energy spectrometry). The magnet is used to select the precursor... 

Bozorgzadeh, M. H., Morgan, R. P. and Beynon, J. H. (1978) Application of mass-analysed ion kinetic energy spectrometry (MIKES) to the determination of the structures of unknown compounds, Analyst 103, 613-622. 

Mass spectrometry is suitable for the identification of pyrrolo-benzodiaze-pines and the differentiation of their isomers (1996M1653). A structural distinction can be made easily from their mass spectra or the metastable mass-analyzed ion kinetic energy (MIKE) spectra, produced by their molecular or most intense fragment ions. Established fragmentation pathways have been supported by MNDO and AMI semiempiiical calculations. 

The geometry is less frequently a BE one. It is sometimes called a reverse Nier-Johnson or reverse geometry . This geometry allows an easier analysis of the ion kinetic energy (IKE or MIKE spectrometry). 

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