Migrating myoelectric complex

The influence of the interdigestive migrating myoelectric complex on the gastric emptying of liquids, Gastroenterology 1990, 99, 1275-1282. 

J. L. Barnett, C. Owyang, J. H. Meyer, G. L. Amidon. The influence of the interdigestive migrating myoelectric complex on the gastric emptying of liquids. Gastroenterol. 1990, 99, 1275— 1282. 

Husebye E, Hellstrom PM, Midtvedt T The intestinal microflora stimulates myoelectric activity of rat small intestine by promoting cyclic initiation and aboral propagation of the migrating myoelectric complex. Dig Dis Sci 1994 39 946-956. 

In the GI tract, different hydrodynamic conditions are present, depending on the fasted or the fed state. Contraction patterns are controlled in terms of electromechanical impulses (myoelectric activity) as well as by various hormones (cholecystokinin, secretin, glucagon, motilin, and insulin, for example). In the fasted state, the motility pattern is regulated by the (interdigestive) migrating myoelectric complex [(I)... 

Wang, Z., Zhenya, H., and Chen, J., Chaotic behavior of gastric migrating myoelectrical complex, IEEE Transactions on Biomedical Engineering, Vol. 51, No. 8, 2004, pp. 1401-1406. 

Bardakjian, B.L. and Ahmed, K. 1992. Is a peripheral pattern generator sufficient to produce both fasting and postprandial patterns of the migrating myoelectric complex (MMC) Dig. Dis. Scl, 37 986. 

El-Sharkawy, T.Y. 1983. Electrical activity of the muscle layers of the canine colon. J. Physiol, 342 67-83. El-Sharkawy, T.Y, Markus, H., and Diamant, N.E. 1982. Neural control of the intestinal migrating myoelectric complex a pharmacological analysis. Can. J. Physiol Pharm., 60 794-804. 

Ruckebusch, Y. and Bueno, L. 1977. Migrating myoelectrical complex of the small intestine. Gastroenterology, 73 1309-1314. 

Sarna, S.K., Stoddard, C., Belbeck, L., and Me Wade, D. 1981. Intrinsic nervous control of migrating myoelectric complexes. Am. J. Physiol, 241 G16-G23. 

Sarna, S., Condon, R.E., and Cowles, V. 1983. Enteric mechanisms of initiation of migrating myoelectric complexes in dogs. Gastroenterology, 84 814-822. 

During fasting, both monolithic and multiparticulate dosage forms will be swept rapidly through the small bowel by the migrating myoelectric complex. 

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