Microspheres medications production

Microencapsulation has also been used medically for the encapsulation of live cells and vaccines. Biocompatibility can be improved by the encapsulation of artificial cells and biomolecules such as peptides, proteins, and hormones, which can prevent unwanted immunological reactions that would lead to inactivation or rejection. Microspheres are used for isolating materials until their activity is needed. The biotechnology industry employs microspheres to contain organisms and their recombinant products to aid in the isolation of these products. ... 

Results are presented of some preliminary tests of the irreversible immobilisation of poly(L,L-lactide) microspheres loaded with Triclosan antibacterial agent onto viscose non-woven structures. The research covered the production of a suspension containing microspheres loaded with Triclosan, tests on the bonding of microspheies with the base textile material and a quantitative assessment of the effect achieved (including microbiological tests). These results indicate the potential for development of new technologies for medical textiles. 11 refs. 

Most of the published papers and patents focused on the utilization of the emulsion solvent removal methods in the production of microspheres of the single or the multipurpose types. Majority of investigated microspheres are intended to achieve controlled release of medications by using matrix formers to sustain, or modify drug release by the incorporation of pH sensitive components, adhesive components, temperature sensitive components, or adjuvants to protect the encapsulated... 

Commercially Available Microsphere Products for Human Medical Use 6... 

Another microsphere also made by Biosphere Medical is EmboGold, the microspheres are manufactured with the addition of gold, which is used to provide coloring. This product is specifically not cleared by the FDA for use in uterine fibroid embolization and has been associated with delayed pain and/or... 

Currently, there are two different preparations available on the market glass and resin microspheres (Tables 2.7.1, 2.7.2). In both products °Y is bound to a microparticle. Since these loaded microparticles present no pharmacological effects, rather physico-mechanical ones, they are considered to be medical devices in terms of a therapeutic radioactive implant and not a drug. The glass microspheres are available in USA, Canada, and recently in Europe the resin particles are available worldwide (Gray et al. 1989 Kennedy and Salem 2003 Wollner et al. 1988). 

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