Triacylglycerol transfer protein, microsomal

Assembly of chylomicrons The enzymes involved in triacylglycerol, cholesterol, and phospholipid synthesis are located in Ihe smooth ER. Assembly of the apolipoproteins and lipid into chylomicrons requires microsomal triacylglycerol transfer protein (see p. 229), which loads apo B-48 with lipid. This occurs during transition from the ER to the Golgi, where the particles are packaged in secretory vesicles. These fuse with the plasma membrane releasing the lipoproteins, which then enter the lymphatic system and, ultimately, the blood. 

Wang, Y.M., Rahman, S.M., Nagao, K., Han, S.Y., and Yanagita, T. (2003) Conjugated Linoleic Acid Reduces Hepatic Microsomal Triglyceride Transfer Protein Activity and Hepatic Triacylglycerol Mass in Obese Rats, J. Oleo Sci. 52, 129-134. 

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