Microgels, nanocapsules

Keywords Confined reaction environment Heterophase polymerization Microgels Miniemulsion Nanocapsules Nanoparticles... 

Gu, Z., Dang, T.T., Ma, M., Tang, B.C., Cheng, H., Jiang, S., 2013. Glucose-responsive microgels integrated with enzyme nanocapsules for closed-loop insulin delivery. ACS Nano 7, 6758—6766. 

Drug delivery methods include oral administration, transdermal absorption, injection (subcutaneous, intravenous, and intramuscular), sprays, insert (suppositories) implantation (subcutaneous, brain, bone), patches (oral or nasal, mucosa, and dentin) [13]. When gels are used for DDS, the shape and size considered will depend on the method of administration. For example, gel particles must be less than several hundred nm for injection. For this purpose, microcapsules, nanocapsules, microgels, coacervates, and microspheres are used. 

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