Micellar electrokinetic chromatograph migration times

Chromatographic and related electrophoretic methods for the separation of transition metal complexes or their ligands were reviewed . Micellar electrokinetic chromatography (MEKC) presents a new development in the field of capillary zone electrophoresis (CZE). The use of micellar solutions expands the application of CZE to electronically neutral solutes, as well as charged ones. Thus, electrically neutral / -diketonates Cr(dik)3, Co(dik)3, Rd(dik)3, Pt(dik)2 and Pd(dik)2 were separated by CZE in micellar solutions of sds. A linear log-log relationship was found between the distribution coefficient and the partition coefficient of the complex between dodecane and water, which was used for prediction of both the distribution coefficients and the migration times of different metal complexes . 

Micellar Electrokinetic Capillary Chromatography. Surfactants that form micelles in solution are added to the buffer in the capillary. When the solute is injected, it partitions itself between the buffer and the micelle. Migration of the solute depends on the amount of time it spends in the micelle versus the time it spends in the buffer. Therefore, the separation of analytes occurs due to differences in the partition coefficient between the two phases, much like in a chromatographic process. 

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