Metrizoate

Value is for metrizoate sodium (Isopaque, Sterling-Winthrop Pharmaceuticals) (14). 

Metrizoic acid Diazomethane Diazepam Epirizole Methoxsalen Pyrimethamine Dibenzo[a,el cycloheptadiene Butriptyline... 

Metoclopramide HCI Metrizoic acid Paramethadione Pentapiperide methosulfate... 

C11H9I3N2O4 117-96-4) see Metrizoic acid aminoacetaldehyde diethyl acetal (C H 5N02 645-36-3) see Thiamazole p-aminoacetanilide... 

The first modern hydrophilic nonspecific iodinated CA was diatrizoic acid, which, formulated as a sodium and/or meglumine salt, is still used. This agent was first synthesized in 1953 [1]. Osmolality for this compound, at concentrations compatible with imaging (ie. 300-370 mgl mL" ), is about 5-7 times that of plasma (1500-2100 mOsm kg H2O). Other HOCA such as iothalamate, metrizoate and ioxithalamate, were synthesized and marketed over the next few years. In an attempt to reduce the osmolality of the injected solution and thus reduce pain and haemodynamic disturbances, metrizamide, a compound resulting from the condensation of metrizoic acid and glucosamine, was synthesized. It was the first nonionic CA. 

Histopaque and Lymphoprep consist of a mixture of Picoll and sodium metrizoate. In cell mixtures, the density can be at usted to enrich one cell type at the expense of another. 

High-osmolar ionic monomers (for example amido-trizoate (diatrizoate) iodamide, iotalamate, ioxitala-mate, metrizoate)... 

Metrizamide metrizoate Coaguiation necrosis in celiac and renal vasculature ... 

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