Metoclopramide Aspirin

Metoclopramide Aspirin Increased rate and extent of absorption of aspirin in patients with migraine Can be used therapeutically... 

Albumin, aminophylline, aspirin, heparin, insulin, metoclopramide, NSAIDs, muromonab-CD3 (OKT3), opiates, penicillins, propafenone, quinidine, senna, sulfonamide antimicrobials, and vancomycin... 

Aspirin To facilitate digestive tract absorption, aspirin is usually combined with metoclopramide. Self-medication is widespread. Its efficacy versus placebo is well documented, generally at the dose of 1 g/d. 

Fixed dose combination of metoclopramide with systemically absorbed drugs except fixed dose combination of metoclopramide with aspirin/paracetamol. 

METOCLOPRAMIDE ANTIPLATELET AGENTS -ASPIRIN T aspirin levels with metodopramide T absorption of aspirin Watch for early features of salicylate toxicity... 

A number of ANALGESICS can be used to offset the pain of the attack, including aspirin, codeine and paracetamol, and these are often incorporated into compound preparations together with a variety of other drugs and drug types, e.g. caffeine, buclizine, doxylamine, isometheptene, pizotifen. Sometimes drugs with antinauseant or ANTIEMETIC properties are included, e.g. cyclizine and metoclopramide. 

Noninterfering acetaminophen, amitriptyline, aspirin, atenolol, camazepam, carbamaze-pine, chlorimipramine, chlorthalidone, clonetzepam, cortisone, desipramine, diazepam, halazepam, hydrochlorothiazide, hydrocortisone, imipramine, lorazepam, maprotiline, meperidine, methylphenobarbital, methylprednisolone, metoclopramide, midazolam, morphine, nalorphine, naloxone, nitrazepam, nortriptyline, oxeizepam, oxprenolol, phenobar-bital, phenji oin, pindolol, prazepam, prednisolone, prednisone, primidone, prochlorperazine, propranolol, salicylic acid, temazepam... 

Noninterfering metabolites, acetaminophen, aspirin, ( clophosphamide, dextropropo -phene, diamorphine, dihydrocodeine, doxorubicin, methotrexate, metoclopramide, morphine, phenobarbital, prednisone, proceu bazine, prochlorperazine, vincristine... 

Metoclopramide increases the rate of absorption of aspirin and tolfenamic acid. Conversely, metoclopramide reduces the bioavailability of ketoprofen. 

The clinical importance of the reduction in ketoprofen levels is unknown, but the authors of the study recommend that ketoprofen (and possibly other NSAIDs that are poorly soluble) should be t en 1 to 2 hours before metoclopramide. Conversely, for aspirin, tolfenamic acid, and other NSAIDs, metoclopramide can be used to increase the rate of absorption, and therefore possibly speed up the onset of analgesic effect in conditions such as migraine. 

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