Methylated organotin compound

High performance liquid chromatography coupled with hydride generation-direct current plasma emission spectrometry has been used for trace analysis and speciation studies of methylated organotin compounds in water [263],... 

The preparation of volatile derivatives makes the ionic organotin compounds amenable to evaporative separation techniques (purge and trap or gas chromatography). Hydride formation in dilute aqueous solutions is becoming a routine method for determination of methyltins [101, 104, 105, 109, 110], methyl- and butyltins [100, 111, 112], and phenyland various other organotin compounds [77, 113, 114] to form the volatile hydrides... 

In addition to synthetic organotin compounds, methylated tin species can be produced biologically in the environment. Figure 12.6 gives some examples of the many known organotin compounds. 

S2fi) Sisido, K., Kozima, S., Takizawa, K. Optically active organotin compounds. Preparation and reaction of (l-Methyl-2,2-diphenyl-cyclopropyl)trimethytin. Tetrahedron Letters 1967, 33. - Gas Chromatog. Abstr. 1967, 1112. 

Recently, an alternative synthesis route has been described that prevents the use of both the expensive and moisture-sensitive Re207 as well as of the toxic organotin compounds. This route uses acetyl perrhenate as the rhenium source and methylzinc acetate as the methylating agent. Acetyl perrhenate can be obtained by treatment of... 

Plzak ei al. [220] extracted organotin compounds into hexane and derivitivised by methylation with a Grignard reagent or reduced to tin hydride with sodium borohydride prior to determination by gas chromatography-mass spectrometry. 

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