4-Quinolinol, 2-methyl

Nitriloacetic acid reacts with vanadium-(m). -(iv), or -(v) oxides to form oxovanadatranetrionic acid (38). The crystal structure of [VO(CjQHgNO)2] (CjgHgNOH = 2-methyl-8-quinolinol) has shown that the vanadium atom has a five-co-ordinate trigonal-bipyramidal environment, with three oxygen atoms in the equatorial plane and the two nitrogen atoms of the bidentate ligand in the apical positions. The optimum conditions for the formation of a 1 2 2 vanadium(iv)-morin-4-aminoantipyrine system have been described as pH 5, a tenfold excess of morin (39), and a 3300-fold excess of 4-amino-antipyrine. ... 

VO(oxine)2] (138) and [VO(oxine)2py]-C6H6 (140), prepared by a ligand displacement reaction (equation 61), had v(V==0) = 963 and 945 cm and pcS = 1.75 and 1.64 BM, respectively. When 8-quinolinol is replaced by 2-methyl-8-quinolinol in reaction (61), [VO(2-Me-oxine)2] is obtained, with v(V=0) = 970 cm-1. Complexes (138) and (140) react readily with 02 and a diamagnetic dinuclear pi-oxo Vv species [(oxine)2—OV—O—VO(oxine)2] is produced.826 Nitrobenzene and 2-nitrosobiphenyl also react in a similar manner in THF giving the same complex. With p-benzoquinone a dinuclear diamagnetic Vv complex [(oxine)2OVOC6H4OVO(oxine)2] is obtained. 

The stability constants [470] of La- and Ce-8-quinolinol complexes wese studied in a dioxane-water mixture. Freasieb et al. [471] reported the stability and thermodynamic data for La, Ce, Pr, Nd, Sm, Gd and Er complexes of 8-quinolinol-5-sulphonic acid. These complexes were found to be less stable than those of 8-quinolinol and 2-methyl-8-quinolinol. 

Compounds (20) and (21) undergo electrochemical oxidation to give films of poly(2-methyl-8-quinolinol) and poly(S-quinolinol) on a variety of metal substrates.60 Copper(II) can be com-plexed from aqueous media, but cobalt(II) requires an organic medium. X-ray photoelectron spectroscopy shows the copper(II) complex of films derived from (20) to be complexed to both N and O and also shows that water is absent from the primary coordination sphere. However, for cobalt(II) on the polymer derived from (21), water is present in the primary coordination shell. 

Therapeutic Function Antibacterial Chemical Name 5,7-Dichloro-2-methyl-8-quinolinol Common Name Hydroxydichloroquinaldine Chloroquinaidol Chemical Abstracts Registry No. 72-80-0... 

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