2-Methyl-l,4,7-triazacyclononane

Methyl-l,4,7-triazacyclononane, cobalt(III) hexaamines, 35 144 Meyer reaction... 

Mason and Peacock synthesized the cyclic terdentate, R-(-)-2-methyl-l,4,7-triazacyclononane and its Co(III) complex, [Co(R-MeTACN)(69). Figure 7 shows a perspective drawing of the complex ion, T-)cgo CCo(R MeTACN)in its iodide pentahydrate crystals. The complex ion has D symmetry by the requirement of... 

The CD spectra of bis[(R)-2-methyl-l,4,7-triazacyclononane]cobalt(III), [Co(R-metacn)2], were studied by Mason and Peacock For this complex, five... 

Upon recrystallization, [Ni(tpzlmtacn)]2+ affords [Ni(L)(MeCN)]2+ (L = l,4-bis(pyrazol-l-ylmethyl)-l,4,7-triazacyclononane) via a N-dealkylation reaction and loss of a pendent arm.1420 More rational routes to Ni complexes of tacn ligands with only one or two pendent arms have been developed.1431,1432 In [Ni(L)(X) ]x (e.g., L= l-(3-aminopropyl)-l,4,7-triazacyclononane (n = 2) or l-(l-methylimidazol-2-ylmethyl)-l,4,7-triazacyclononane (n = 2) or l,4-bis(l-methyl-imidazol-2-ylmethyl)-l,4,7-triazacyclononane (n = 1), the coordination sphere is completed by additional ligands that bind either terminal (X = C1 , H20) or bridge two metal ions (X = N3 , OH, oxalate). The Ni11 complex of l,4-bis(2-pyridylmethyl)-l,4,7-triazacyclononane has been shown to be extremely inert to ligand dissociation in aqueous solution.1433 In (562), the tacn ligand provides a single bidentate arm.1434... 

A cooperative effect of two mononuclear complexes has been observed in the hydrolysis of phosphate mono- or diesters, the reaction order being then two with respect to the metal (343-348). Hydrolysis of methyl para-nitrophenylphosphate diester doubly coordinated to a di-nuclear cobalt(III) complex was reported, and a crystalline compound of dimethylphosphate coordinated to the same cobalt complex was characterized [Co2 (l,4,7-triazacyclononane)2 (0H)2 02P(0CH3)2 ] ... 

GFP hopo ICBP IP3 Ln3+ mal memal MLCK nota oxine par pdta pmea py quin-2 green fluorescent protein hydroxypyridinon(at)e intestinal calcium-binding protein inositol 1,4,5-triphosphate a lanthanide(III) cation malonate methylmalonate myosin light chain kinase 1,4,7-triazacyclononane-l,4,7-triacetate 8- hydroxyquinoline pyridine-2-azo-4 -dimethylaniline propylene-1,2-diaminetetraacetate 9- [2-(phosphonomethoxy)ethyl] adenine pjrridine pjrridyl 8-amino-2- [(2-amino-5-methylphenoxy )methyl] -6-methoxyquinoline-ATJV -tetraacetate 2- [ [2-[his(carboxymethyl)amino]-5-methyl-phenoxy] methyl] -6-methoxy-8- [bis(carboxymethyl) amino] quinoline]... 

Photolysis of the monoazido species [Mn L (acac)L]BPh4 (where L is 1,4,7-triazacyclononane, is its N-methylated derivative, and acac is pentane-2,4-dionate) in the solid state has been demonstrated to yield the six-coordinate nitrido species [Mn L(N)(acac)]BPh4. ... 

Tris-N-functionalization of 1,4,7-triazacyclononane has yielded a variety of sexadentate ligands, which form stable complexes with manganese(II). For example, the l,4,7-tris(2-pyridyl-methyl) derivative gives a complex of type [MnL](C104)2 in which the manganese ion has a... 

Open-chain vinylamine is an identifiable side product during synthesis of 1,4,7-triazacyclononanes, resulting from the side FL -elimination process. Intermediate 82 can be isolated by column chromatography on neutral alumina and subsequently converted to 2-methyl-l,6-ditosyl-l,3,6-triazocane 31 by the addition of either silica gel or HBF4. The reaction also proceeds smoothly under Lewis acid catalysis using BF3 etherate (Equation 9 <1999TL9363>). 

MeOsalen = N,N/-ethylenebis(5-methoxysalicylideneiminate) Me3tacn = /V,/V/,/V//-trimethyl-1,4,7-triazacyclononane MMAO = modified methylaluminoxane MMTP = l-methoxy-2-methyl-l-trimethylsiloxypropene MOCVD = metal organic chemical vapor deposition Ms = mesityl = 2,4,6-trimethylphenyl NBD = norbornadiene NBS = iV-bromosuccinimide NitOH = p-nitrophenol Np = 3-neopentyl OAc = acetate OBz = benzoate... 

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