Methyl 4-hydroxy-3-nitrophenyl acetic acid

Nitrocoumarin and hydroxylamine in ethanol yield a 1 2 adduct (20) (see Section II,A,3) which with mineral acid cyclizes to 5-nitro-2,3-dihydro-indoxazene-3-acetic acid (63).21 With diazomethane, 63 yields the methyl ester and with acetic anhydride the JV-acetyl derivative. Oxidation to indoxazene-3-carboxylic acid is successful using selenium dioxide, whereas hydrogenation in the presence of palladium-charcoal brings about ring opening to j3-amino-j3-(2-hydroxy-5-nitrophenyl)propanoic acid. 

Hydroxy-1 -naphthalenyl)azo]-5-nitrobenzenesulfonic acid, H-00351 [[2-[(2-Hydroxy-1 -naphthalenyl)azo]phenyl] thio]acetic acid, H-00352 6-[2-Hydroxy-3-nitro-5-[(4-nitrophenyl)azo] benzyl]-6-methyl-1,4,8,11-tetraoxacyclotetradecane, H-00389 2-Hydroxy-4-(4-nitrophenylazo) benzoic acid, H-00393... 

DL-a-acetamido-P-hydroxy-p-nitropropiophenone has been prepared from L-(+)-threo-(p-nitrophenyl)-2-aminopropan-l,3-diol and acetic anhydride followed by photooxidation in the presence of acidic KBrOs and HBr. Photosensitized electron transfer reactions of tri-1-naphthyl phosphate and di-1-naphthyl methyl phosphate using 9,10-dicyanoanthracene are reported to lead to the formation of 1,1 -binaphthyl, but no reaction occurs for mono-1-naphthyl and di- or tri-phenyl esters. Irradiation of bis(3,4-methylenedioxyphenyl) methylphosphonate in the presence of DCA induces single electron oxidation followed by intramolecular rearrangement and gives 2-(3,4-methylenedioxyphenyl)-3,4-methylenedioxy-phenyl methylphosponate. ... 

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