Methyl fluoride, reaction

Fig. 4 The total secondary a-deuterium KIE versus the bending vibration contribution to the KIE for the SN2 reactions of methyl fluorides and chlorides with different nucleophiles at 25°C. The open circles are for the methyl chloride reactions and the solid circles are for the methyl fluoride reactions. Data from Poirier et al. (1994), with...

The results in Table 5 show the (ArH/ D)sireich is effectively constant for each leaving group i.e., it varies from 0.66 to 0.69 (by only 0.03) when the nucleophile changes from F to SH in the methyl fluoride reactions and from 0.68 to 0.72 (by only 0.04) when the nucleophile changes from F to SH in the methyl chloride reactions. (/cn/A r ))bend, on the other hand, changes from 0.98 to 1.22, i.e., by 0.24 in... 

---