Methyl dodonates

The Australian hop bush, Dodonaea viscosa—which is also distributed across parts of Oceania, Africa, Southern Asia and Central America—is a rich source of diterpenoids, some of which are pharmacologically active. Ent-labdanes such as hautriwaic add have been shown to produce spasmolytic effects on isolated guinea-pig ileum, involving interference with calcium influx into the smooth muscle cells (Mata et al. 1997). Current attention is focused on a new subtype of clerodane diterpenes to be isolated, known as methyl dodonates (Ortega et al. 2001). 

Ortego, A., Garcia, P. E., Cardenas, J., Mancera, C., Marquina, S., Garduno, M. L. C. and Maldonado, E. 2001, Methyl dodonates, a new type of diterpenes with a modified clerodane skeleton from Dodonaea viscosa, Tetrahedon 57 2981-2989. 

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