Methyl diphenylacetate

Other nucleophiles reported to react under photoinitiation are carbanions derived from ethyl phenylacetate [80,82], and methyl diphenylacetate... 

Ethyl phenylacetate and even the tertiary carbanion methyl diphenylacetate gave 84 and 42%, respectively, of the disubstitution product in their reaction with 2,6-dibromopy-ridine179. However, only monosubstitution product at position 4,134 was obtained in 70% yield in the reaction of 4,7-dichloroquinoline (133) with pinacolone enolate ion (equation 90)179. 

Decarbonylation and Decarboxylation - The photochemical reactions between carboxylic acids such as formic and trifluoroacetic acid and silica surfaces have been studied. The irradiation of diphenylacetic acid in acetonitrile with acridine results in the decarboxylation and the formation of the adduct (102). When the two achiral compounds, acridine and diphenylacetic acid, are cocrystallized a chiral two component molecular crystal is obtained in which the components are present in a 1 1 ratio. Both (—)- and (+)- crystals can be obtained. This crystalline material is photochemically reactive and irradiation brings about decarboxylation and formation of the adduct (102) with an ee of 35%. This compound is accompanied by a low yield of (103) which is formed exclusively on irradiation of the reactants in acetonitrile solution.Photochemical decarboxylation can be brought about by the irradiation of benzilate (104)/ methyl viologen pairs. ... 

Cyclopropylmagnesium bromide is reactive enough to transform esters to the corresponding tertiary alcohols, albeit in moderate yields only. This has been utilized in a couple of cases. Thus, when ethyl diphenylacetate and methyl dicyclopropylacetate were used as electrophiles, l,l-dicyclopropyl-2,2-diphenylethanol (6) and 1,1,2,2-tetracyclopropylethanol (7), spectively, were both isolated in less than 50% yield. 

The direct replacement of chlorine in 2-chlorotetrahydrothiophene by means of MeSH leads to low yields of (339). However, reaction with diphenylacetic acid and EtjN gives the diphenylacetic ester which can be converted to (339) in excellent yield by MeSH. Alternatively, 2-mercaptotetra-hydrothiophene can be prepared by the thiourea method (CHEC-I) and methylated to give (339) <92CB1641>. Deprotonation of (339) with Bu"Li at —30°C gives the 2-lithio derivative this reacts with a variety of electrophiles (alkyl halides, carbonyl compounds) to form (340) (Scheme 69). 

Ethyl p-hydroxybutyrate Ethyl DL-3-hydroxybutyrate. See Ethyl 3-hydroxybutyrate Ethyl hydroxydiphenylacetate Ethyl 2-hydroxy-2,2-diphenylacetate Ethyl a-hydroxydiphenylacetate. See Methyl benzilate 2-(N-Ethyl-N-2-hydroxyethylamino) ethanol. See N-Ethyidiethanolamine 2-[[4-[Ethyl (2-hydroxyethyl) amino] phenyl] azo]-6-methoxy-3-methylbenzothiazolium methyl sulfate. See Basic blue 41 Ethyl (P-hydroxyethyl) aniline N-Ethyl-N-(2-hydroxyethyl) aniline. See Phenylethylethanolamine Ethyl hydroxyethyl cellulose CAS 9004-58-4 INS467... 

CAS 76-89-1 EINECS/ELINCS 200-991-1 Synonyms Benzeneacetic acid, a-hydroxy-a-phenyl-, methyl ester Benzilic acid methyl ester Ethyl hydroxydiphenylacetate Ethyl 2-hydroxy-2,2-diphenylacetate Ethyl a-hydroxydiphenylacetate Ethyl a-phenylmandelate Hydroxydiphenylacetic acid, methyl ester Methyl benzillate Methyl diphenylglycolate Methyl hydroxy (diphenyl) acetate Methyl-2-hydroxy-2,2-diphenyl acetate Empirical C15HI4O3... 

Dimethylaminoethyl methacrylate methyl chloride quat. diphenylacetic acid mfg. 

The dianion of diphenylacetic acid (or 2-phenylpropanoic acid) was generated by reaction of sodium naphthalenide. This C-nucleophile opened the three-membered ring of N-benzylaziridine to give 4-(N-benzoylamino)-2,2-diphenylbutanoic acid (or 4-(N-benzoylamino)-2-methyl-2-phenylbutanoic acid after hydrolysis 4.86, R = Ph, Me respectively). ... 

HgO and dimethylform-amide, treated slowly with methyl iodide, and stirred 6 hrs. at 20° methyl a-methoxy-diphenylacetate. 

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