Methyl 2,4-dihydroxy-3,5-dichloro-6-methylbenzoate

Methyl 3,5-dichloroorsellinate, Methyl 2,4-dihydroxy-3,5-dichloro-6-methylbenzoate... 

Several substituted dihydroxybenzoic acids have been examined by the yeast oedema and granuloma pellet test in rats , and anti-inflammatory activity appears to be restricted to the substituted 2,6-dihydroxy compounds. The presence of a halogen at Cg and Cj produces activity which is further increased when a methyl or benzyl group is also present at G4. 4-Benzyl-2,6-dihydroxybenzoic acid is also active, despite the absence of halogen at Cg or C5. The most potent compound of all is 3,5-dichloro-2,6-dihydroxy-4-methylbenzoic acid XIII). Whenever anti-inflammatory activity has been... 

---

See also in sourсe #XX -- [ ]

---