Methyl amentoflavone

Araucaria cunninghamii Aitonex Sweet Na Yang Shan (shoot) Methyl communate, methyl isocupressate, methyl acetyl-isocupressate, labdadien, diacetate, methyl amentoflavone.57 Treat skin diseases. 

Cephalotaxus wilsoniana Hayata (twigs) Biflavones I-7,4, II-7-T ri-O-methyl-amentoflavone (16) taiwanhomoflavone B (246). Cytotoxic activity Inhibitory effects against KB oral epidermoid carcinoma and Hepa-3B hepatoma cells. Kuo et al., 2002[36]. 

Podocarpus latifolius (Thunb.) R. Br. ex Mirb. (leaves) Biflavones Amentoflavone (1) I-7,4 -di-O-methyl-amentoflavone (= ginkgetin) (7) heveaflavone (18) I-7,4, II-7,4 -tetra-O-methylamentoflavone (19). Used in Zulu traditional medieine. Ginkgetin is an aetive leishmanicidal compound. Ginkgetin also showed a good antitrypanosomal activity. Antimicrobial activity. Fozdar et al., 1989[483] Abdillahi et al., 2008[484], 2010[485]. 

Podocarpus taxifolia H.B.K. [= Prumnopitys montana (Humb. Bonpl. ex Willd.) de Laub.] Heveaflavone (18) bilobetin (3) podoearpusflavone A (6) sequoiaflavone (2) I-2,3-dihydroamentoflavone (31) I-7-0-methyl-I-2,3-dihydroamentoflavone (32) podoearpusflavanone (40) I-5,7,4, II-5,7,4 -hexa-0-methyl-amentoflavone (= dioonflavone) (22). Antioxidant and anti-inflammatory activities. Kumar-roy et al., 1987[467] Abdillahi et al., 2010[485,487]... 

The occurrence of biflavonyl compounds in ferns had not been documented before 1979 when partially methylated amentoflavone derivatives isoginkgetin (259), sciadopitysin (260) and others (261, 262), were isolated from Osmunda japonica (171). Hegoflavones A (263) and B (264) isolated from Alsophila spinulosa are the first examples of a new type of biflavonoid linked by a 6,6 "-bond (172). 

I-3, II-8)-Biliquiritigenin 1-2,3,11-2,3 -T etrahydro-amentoflavone Semecarpuflavanone Jeediflavanone Galluflavanone I-4 -0-Methyl-1-2,3,11-... 

I-7,II-7-Di-0-methyl-I-2,3,II-2,3-tetrahydro-amentoflavone Semeoarpetin Nallaflavone 11-3, 4 substituent -O-CH2-O- (methylenedioxyl). 

Cycas revoluta Thunb. (leaflets) (leaves) Amentoflavone (1) hinokiflavone (235) sotetsuflavone (5) 2,3-dihydroamentoflavone (31) 1-2,3-dihydrohinokiflavone (241) (I-2> ,II-25)-1-4, II-4 -di-0-methyl-I-2,3,11-2,3-tetrahydroamentoflavone (= tetrahydroisoginkgetin) (54) l-4 -0-niethyl-I-2,3,II-2,3- tetrahydroamentoflavone (52) l-4 -0-methyl-I-2,3-dihydroamentoflavone (34). Moderately active antibacterial biflavonoids (see C. circinalis). Geiger and de Groot Pfleiderer, 1971 [446] Moawad etal.,2010[77]. 

Libocedrus bidwillii Hook f. Bifluvones Amentoflavone (1) sequoiaflavone (2) 1-2,3-dihydroamentoflavone (31) 1-7-0-methyl-I-2,3-dihydroamentoflavone (32). Markham et al., 1990[461]. 

Many other flavonic compounds have been reported to exhibit an interesting antiulcer effect mecyadanol, (+)-cyanidanol-3, (+)-catechin, 3-0-methyl-(+)-catechin, 3-methoxy-5,7,3 ,4 -tetrahydroxyflavan, apigenin-7,4 -diorthomethylether, hesperidin, and amentoflavone [118-121],... 

The cupressuflavones (1-8,11-8 biflavonoids) (3) are also a small group of compounds compared to the amentoflavones, and usually co-occur with them (Table 7.6.2). Cupressuflavone and its variously C-4 and C-7 methylated derivatives are prominent constituents of the Araucariaceae and Cupressaceae (125). Curiously they have not yet been found in the Thxodiaceae. All of these compounds carry a 5,7,4 -substitution pattern. One flavanone-flavone dimer, mesuferrone-B (307), and a biflavanone, mesuferrone-A (308), have been described from Mesuaferrea,... 

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