4- Methoxy-3-nitropyridines, reaction with

The reaction of 4-methoxy-3-nitropyridines 129 with guanidine under similar conditions results in 3-aminopyrido[3,4-e]-l,2,4-triazine 1-oxides 130 (76MI). 

Nitropyridine and 4-nitropyridine A-oxide have been shown to react with iso-prene, 1-methoxy-l,3-butadiene, and Danishefsky s diene to produce isoquinoline cycloadducts. One asymmetric and asynchronous transition state (TS) was detected between the reactants and the cycloadduct with isoprene and two TS were observed when 1-methoxy-l,3-butadiene and Danishefsky s diene were used. The Diels-Alder reaction of highly substituted dihydropyridines with e-deficient alkenes produced highly substituted isoquinuclidines with high stereo- and regio-selectivity. The Diels-Alder cycloaddition of cyclopentadiene to lithium ion encapsulated [60]fullerene proceeds at a higher rate than with that of empty [60]fullerene. ... 

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