Methanococcus igneus

Ciulla, R.A., S. Burggraf, K.O. Stetter, and M.F. Roberts (1994). Occurrence and role of di-/Myoinositol-1-1 -phosphate in Methanococcus igneus. Appl. Environ. Microbiol. 60 3660-3664. 

DIP is a complex solute that was first noted as a major solute in Pyrococcus woesei (Scholz et al., 1992) and Methanococcus igneus (Ciulla et al., 1994). In P. woesei, DIP accumulates in quantities comparable to intracellular... 

Two different pathways for the synthesis of DIP have been investigated in Pyrococcus woesei and Methanococcus igneus. In P. woesei the synthesis was reported to proceed via two steps glucose 6-phosphate is converted into... 

L-OT3 o-inositol 1-phosphate, two molecules of which are subsequently condensed to form di-ffiyo-inositol l,l -phosphate. In Methanococcus igneus the final step involves the condensation of CDP-inositol and myo-inositol to produce DIP and CMP. Inositol 1-phosphate is activated to CDP-inositol by the action of a CTP-inositol cytidylyltransferase. Glucose 6-phosphate is converted to inositol 1-phosphate, part of which is hydrolyzed to wyo-inositol. ... 

Pyrococcus endeavori (unpublished results ), hydrogenases from Methanococcus jannaschii and the extreme thermophile Methanococcus igneus, a-glucosidase from P. furiosus, glyceraldehyde-3-phosphate dehydrogenase from Thermotoga... 

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