Methanesulfonic acid methyl ester

Chem. Abstr. Name . Methanesulfonic acid, methyl ester... [Pg.1059]

METHANESULFONIC ACID. ETHYL ESTER METHANESULFONIC ACID, METHYL ESTER... [Pg.233]

Methyl mesylate, methanesulfonic acid methyl ester, MMS. [Pg.369]

SYNS as-DLMETHYL SULPHATE METHANE-SULPHONTC ACID METHYL ESTER METHYL ESTER of METHANESULFONIC ACID METHYL ESTER of METHANESULPHONIC ACID METHYL METHANE-SULFONATE n METHYL METHANESULPHONATE METHYL METHANSULFONAT (GERMAN) METHYL METHANSULFONATE METHYL METHANSULPHON-ATE MMS NSC-50256... [Pg.933]

Synonyms as-Dimethyl sulfite Methanesulfonic acid, methyl ester Methyl ester of methanesulfonic acid Methyl mesylate Methyl methansulfonate MMS... [Pg.2654]

Synonyms Methanesulfonic acid, trifluoro-, methyl ester Trifluoromethanesulfonic acid, methyl ester Empirical C2H3F3O3S Properties Colorless to brn. liq. sol. in 95% ethanol insol. in water reacts exothermically with DMSO m.w. 164.10 sp.gr. 1.450 (20/4 C) b.p. 94-99 C flash pt. 38 C ref. index 1.3244 (20 C) Toxicology Toxic by inh., ing., skin contact corrosive causes burns extremely destructive to tissues of eyes, skin, mucous membranes, upper respiratory tract risk of irreversible effects inh. may cause spasm, inflamm./edema of larynx/bronchi, chem. pneumonitis, pulmonary edema may cause burning... [Pg.2696]

Methyl triflate Methyl trifluoromethanesulfonate Methanesulfonic acid, trifiuoro-, methyl ester (8,9) (333-27-7)... [Pg.90]

Pyrrole- and indole-carboxylic acid chlorides react with dialkyl- and diaryl-cadmium to yield the ketones and it is noteworthy that the reaction of the anhydride of indole-2,3-dicarboxylic acid with diphenylcadmium produces 3-benzoylindole-2-carboxylic acid and not its isomer (53JCS1889). The ability of l-methylindole-2-carboxylic acid to react with nucleophiles is enhanced by conversion into the mixed anhydride with methanesulfonic acid. The mixed anhydride reacts with carbanions derived from diethyl malonate and from methyl acetate to yield the indolyl (3- keto esters (80TL1957). [Pg.288]

Methyl 4,6-0-benzylidene-3-deoxy-a-D-ribo-hexopyranoside (56) was benzoylated, debenzylidenated, and partially p-toluenesulfon-ylated to 57 this was converted into 58 by reaction with sodium iodide, followed by catalytic reduction. The methanesulfonate of 58 was converted into 59 by reaction with sodium azide in N,N-dimethylformamide, and 59 was converted into 4-azido-3,4,6-trideoxy-a-D-xylo-hexose (60) by acetolysis followed by alkaline hydrolysis. Reduction of 60 with borohydride in methanol afforded 61, which was converted into 62 by successive condensation with acetone, meth-anesulfonylation, and azide exchange. The 4,5-diazido-3,4,5,6-tetra-deoxy-l,2-0-isopropylidene-L-ara/uno-hexitol (62) was reduced with hydrogen in the presence of Raney nickel, the resultant diamine was treated with phosgene in the presence of sodium carbonate, and the product was hydrolyzed under acidic conditions to give 63. The overall yield of 63 from 56 was 4%. The next three reactions (with sodium periodate, the Wittig reaction, and catalytic reduction) were performed without characterization of the intermediate products, and gave (+)-dethiobiotin methyl ester indistinguishable from an authentic sample thereof prepared from (+)-biotin methyl ester. [Pg.212]

First the hydroxy group is protected as the TBS ether. In the second step lithium diisopropylamine (EDA) is used to deprotonate the a-carbon and the resulting lithium enolate is trapped as trifluoro-methanesulfonic acid ester. In the last reaction, palladium catalysis is used to introduce the carbon monoxide. In the presence of methanol this intermediate directly yields the methyl ester. [Pg.185]

S-Methy methanethiosulfonate Methanesulfonic acid, thio-, S-methyl ester (8) Methanesulfonothioic acid, S-methyl ester (9) (2949-92-0)... [Pg.52]

Methyl-2-pyridyl triflate Methanesulfonic acid, trifluoro-, 4-methyl-2-pyridinyl ester (13) (179260-78-7)... [Pg.176]

In addition, final salt-forming steps can introduce genotoxic impurities. Some examples include formation of methyl chloride as a side reaction of hydrochloric acid in methanol, or esters of methanesulfonic acid as the by-product from the methanesulfonic acid salt formation step in alcoholic solvents. ... [Pg.17]

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