Methamizole sodium

Nevertheless, the most widely used derivative in medicine is methamizol sodium (although it is prohibited in some countries) as well as combined drugs on its base in particular, baralgin, which represents a combined drug based on methamizol sodium with the spasmolytic 4 -(ethoxypiperidine)carbomethoxybenzophenone and the ganglionic blocker 2,2-diphenyl-4-piperidylacetamide. 

Metamizole sodium Methamizole sodium, l-phenyl-2,3-dimethyl-4-methylaminopyra-zolone-5-A -sodium methansulfonate (3.2.16), is synthesized in a multi-stage synthesis from acetoacetic ester and phenylhydrazine. Their reaction leads to the formation of 1-phenyl-3-methylpyrazolone-5 (3.2.9). Methylation of this product with methyl iodide gives 1-phenyl-... 

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