Metallo aldimines

H. M. Metallo aldimines. A masked acyl carb-anion./. Org. Chem. 1974, 39, 600-604. 

Tetramethy Ibutyl isocyanide Syntheses via metallo aldimines... 

Alder s. Diene syntheses Aldimines s. Metallo aldimines Aldol condensation s. a. Retroaldol reaction —, intramolecnlar -, diazoketols, cyclic by - 26,938 Aldol-type condensation, intramolecnlar, to heterocycles 26,935 Aldonolactones... 

Dilithium tetrachlorocuprate is recommended as an additive for cross coupling of Grignard compounds with tosylates even allylic and benzylic acetates give good yields . a-Methylene-ketones, -carboxylic acids and -lactones have been prepared via sulfides and sulfoxides. A convenient and general synthesis of acetylene derivatives from boranes via the reaction of iodine with lithium 1-alkynyltriorganoborates has been published ar-Nitrostyrenes can be easily obtained by a Wittig synthesis with formaldehyde in an aqueous medium . A new synthesis of unsym. ketones by reaction of dialkyldiloroboranes with lithium aldimines has recently been published . Metallo aldimines have also served for the synthesis of a variety of other compound classes such as a-hydroxyketones, a-keto acids, nitriles, and for the asym. synthesis of a-amino acids . Polycondensations of malononitriles with benzylic chlorides have been carried out quantitatively under mild conditions in dimethyl sulfoxide with triethylamine as acid acceptor . Carbonyl compounds can react with dibromoacetonitrile to yield a-bromo esters with additional carbon atom . ... 

Alder s. Diene syntheses Aldimines (s. a. Metallo aldimines)... 

Aliphatic organomagnesium or organolithium reagents add to 1,1,3,3-tetramethylbutyl isocyanide to give the corresponding metallo-aldimine (150), another acyl carbanion equivalent, which reacts with a range of electrophiles in the normal manner. 

Rh(l)-catalyzed [2-I-2-I-2] cyclotrimerization of 1,6-diynes (e.g., 1391 and 1394) with monoynes (e.g., 1392) in combination with stereospecific Ag(i)-catalyzed aldimine (metallo)azomethine ylide — cycloaddition cascades affords rapid access to complex heterocyclic benzene derivatives 1393 and 1395 in one-pot processes with the generation of five new bonds, four stereocenters and three rings (Schemes 266 and 267) <2000T8967>. 

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